National guidelines shape prescribing decisions by accounting for treatment goals and therapeutic clinical data in a disease state. In addition to efficacy and safety profiles of pharmacologic agents, physicians often consider a drug’s pharmacokinetics in their prescribing decisions. Pharmacokinetics, sometimes abbreviated as “ADME” for its component processes, describes how a drug is absorbed (“A”), distributed (“D”), metabolized (“M”) and excreted (“E”) by the body.